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Twenty One Hotel

Rome, Italy
Great location. Fantastic service.

Located on Via Cola di Rienzo, the hotel is situated in the elegant Prati district, home to the Vatican and Saint Peter's Basilica. Vatican City can be reached in around 15 minutes on foot and Piazza del Popolo and Piazza di Spagna are also within walking distance. The hotel is a charming modern boutique hotel with 86 rooms. Guests are welcomed in the lobby with 24-hour reception, 24-hour check-out service and a hotel safe. A bar and restaurant are also available. The hotel also offers a laundry service and garage parking facilities. The en suite rooms are elegant and feature attention to detail. A continental breakfast buffet is available in the bright breakfast room. The Wine Bar serves the best champagne and summates wines.

Located on Via Cola di Rienzo, the hotel is situated in the elegant Prati district, home to the Vatican and Saint Peter's Basilica. Vatican City can be reached in around 15 minutes on foot and Piazza del Popolo and Piazza di Spagna are also within walking distance. The hotel is a charming modern boutique hotel with 86 rooms. Guests are welcomed in the lobby with 24-hour reception, 24-hour check-out service and a hotel safe. A bar and restaurant are also available. The hotel also offers a laundry service and garage parking facilities. The en suite rooms are elegant and feature attention to detail. A continental breakfast buffet is available in the bright breakfast room. The Wine Bar serves the best champagne and summates wines. 

Most popular facilities

  • Free WiFi
  • Air Conditioning
  • Bar
  • Facilities for Disabled Guests
  • Family Rooms
  • Non Smoking Rooms
  • Room Service
  • Wifi
    • Facilities
      • Air conditioning
      • Designated smoking area
      • Facilities for disabled guests
      • Family rooms
      • Free WiFi
      • Heating
      • Lift
      • Newspapers
      • Non smoking rooms
      • Outdoor furniture
      • Room service
      • Safety deposit box
      • Shared lounge/TV area
      • Shuttle service
      • Shuttle service (additional charge)
      • Soundproof rooms
    • Food and Drink
      • Bar
      • Breakfast in the room
      • Good coffee!
      • Kid meals (Additional charge)
      • Restaurant (à la carte and buffet)
      • Snack bar
    • Entertainment
      • Children television networks

Other information

  • 24hr Reception
  • Concierge service
  • Electric vehicle charging station
  • Emergency cord in bathroom
  • Express check-in/check-out
  • Laundry (Additional charge)
  • Luggage storage
  • Parking garage
  • Pets are not allowed
  • Secured parking
  • Toilet with grab rails
  • Tour desk
  • Wheelchair accessible

Please note that Tourist City Tax applies to all stays in Italy and is payable directly to the hotel.

The small cost can vary depending on star rating and is charged per person per night.

Points of interest

  • Ciampino Airport 40 minutes
  • Rome Fiumicino Airport 40 minutes
To make booking a cheap holiday at Twenty One Hotel in Rome easier for you, we provide a range of different payment options.To find out if you can book Twenty One Hotel with a low deposit holiday option or to check if you can grab a last minute holiday deal, please click the "Price and Availability"button above.
A selection of available rooms is shown below. There may be more options available, shown after you've made your flight selection.
  • Family Room
  • Junior Suite
  • Twin Room
  • Double Room
  • Double or Twin Room
  • Deluxe Double Room
  • Triple Room
  • Quadruple Room
  • Deluxe Double or Twin Room
    • Number of bedrooms: 1
    • Bathroom
    • Shower
    • Hairdryer
    • Wi-fi
    • Internet access
    • Direct dial telephone
    • Minibar
    • Safe
    • Wheelchair-accessible
  • Single Room
    • Number of bedrooms: 1
    • Bathroom
    • Shower
    • Hairdryer
    • Wi-fi
    • Internet access
    • Direct dial telephone
    • Minibar
    • Safe
    • Wheelchair-accessible
  • Economy Double or Twin Room
    • Number of bedrooms: 1
    • Bathroom
    • Shower
    • Hairdryer
    • Wi-fi
    • Internet access
    • Direct dial telephone
    • Minibar
    • Safe
    • Wheelchair-accessible
  • Suite
    • Number of bedrooms: 1
    • Bathroom
    • Shower
    • Hairdryer
    • Wi-fi
    • Internet access
    • Direct dial telephone
    • Minibar
    • Safe
    • Wheelchair-accessible
  • Apartment
    • Number of bedrooms: 1
    • Bathroom
    • Shower
    • Hairdryer
    • Wi-fi
    • Internet access
    • Direct dial telephone
    • Minibar
    • Safe
    • Wheelchair-accessible
  • Double or Twin Room - Two Double Beds
    • Number of bedrooms: 1
    • Bathroom
    • Shower
    • Hairdryer
    • Wi-fi
    • Internet access
    • Direct dial telephone
    • Minibar
    • Safe
    • Wheelchair-accessible
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  • Low Deposit options available
  • Pay Monthly
Guests love...
  • ExcellentBusiness Hotel
  • ExcellentCity Hotel
  • ExcellentLuxury Hotel
  • ExcellentRomantic Hotel

What guests say...

  • Location4.7/5762 reviews

    Great location

  • Service4.3/5724 reviews

    Fantastic service

Good to know...

  • Wonderful sightseeing
  • Friendly service
When to go
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